Heart failure

Researchers have been awarded $31 million to study conduction system stimulation in patients with heart failure

Researchers from various schools, including the VCU School of Medicine, Baylor College of Medicine and University of Utah School of Medicine— received funding of $31 million from the Patient Centered Outcomes Research Institute to study the effectiveness of using conduction system stimulation to treat patients who present heart failure (HF) and conduction system disease.

“We will evaluate a new way of stimulating the heart which we believe has the potential to revolutionize the way we treat patients struggling with abnormal heartbeats,” Kenneth Ellenbogen, MDholder of the chair of cardiology at the VCU School of Medicine and director of clinical studies cardiac electrophysiology and pacing at VCU Pauley Heart Center, said in a Prepared statement. “Once the study begins, this will likely be one of the largest cardiac pacing clinical trials to take place in the world in the next few years.”

Patients with HF and conduction system disease are usually treated with biventricular pacing via a pacemaker, but this approach is not always associated with better outcomes. Conduction system stimulation involves sending electrical impulses directly from a patient’s pacemaker to the electrical signal-conducting cells of their heart.